All is not well at the Zoo-niverse. Animals are disappearing one by one. Things go from bad to worse when Joey Moose, one of the zookeepers goes missing. When Mrs Gideon reports that her python is also on the missing list, reported stolen, Howard is determined to save the day. Howard and Vince stumble across Dixon Bainbridge's secret laboratory and the terrible truth behind his 'experiments' comes to light.