Dr. Wilkes treats identical teenagers with the same rare heart ailment, losing one in the process. Kate treats a 10-year-old who nearly died after sniffing glue, and learns her daughter does the same. Aaron interviews a man for inclusion in a study by Dr. Frank. Diane debates taking maternity leave. McNeil isn't sure whether a man has sentiment or politics at heart when he insists life-saving surgery be taken on his sister, over her same-gender partner's wishes.